The Medabots anime series was adapted from the first two video games, with its robotic combat elements inspired by Plawres Sanshiro. The show is mainly based on Medarot 2, but also references backstory from Medarot 1. Produced by Bee Train, the fifty-two episode series originally aired on TV Tokyo. A thirty-nine episode sequel to the anime series that was produced by Production IG. Both the series are licensed by Nelvana. The Nelvana English dubbed version of Medabots aired on the Fox Kids network and was one of the channel's highest rated new series at the time.

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